Johannes Kepler University in Linz Austria has published a High-Speed Atomic Force Microscopy video of human lectin CLEC4G binding to glycans on a SARS-CoV-2 spike. This video was recorded by Daniel Canena and Peter Hinterdorfer and is, according to the two researchers, the first short film of the active structure the virus uses to attach … Continue reading HS-AFM video of Covid’s Docking Method
The current pandemic is not the only health threat worldwide. Another worry is the increasing antibiotic resistance which increases the fear to run out of effective antibiotics. This is one of the reasons why antimicrobial peptides (AMPs) are gaining more and more interest. The lipopeptide Daptomycin ( DAP ) has been therapeutically used as a … Continue reading High-speed atomic force microscopy highlights new molecular mechanism of daptomycin action
In the article “Multiswitchable photoacid–hydroxyflavylium–polyelectrolyte nano-assemblies” Alexander Zika and Franziska Gröhn describe the development of a novel reversible multi-switchable system consisting of a cationic polyelectrolyte, a hydroxyflavylium molecule (Flavy), and a photoacid.* Ternary assemblies with sizes in the hundred-to-few hundred nanometers range in aqueous solution exhibit a multi-addressable size and shape.* The concept exploits the … Continue reading Multiswitchable photoacid–hydroxyflavylium–polyelectrolyte nano-assemblies