Effective gamma-ray sterilization and characterization of conductive polypyrrole biomaterials

“Conductive polymers, including polypyrrole (PPy), have been extensively explored to fabricate electrically conductive biomaterials for bioelectrodes and tissue engineering scaffolds. For their in vivo uses, a sterilization method without severe impairment of original material properties and performance is necessary. Gamma-ray radiation has been commonly applied for sterilization of medical products because of its simple and uniform sterilization without heat generation.[…]”*

In the article “Effective gamma-ray sterilization and characterization of conductive polypyrrole biomaterials” by Semin Kim et. al cited here, the authors describe the first study on gamma-ray sterilization of PPy bioelectrodes and its effects on their characteristics.

The surface topography and roughness of the PPy and γ-PPy electrodes were analyzed by atomic force microscopy. The experiments were performed using a NanoWorld Pointprobe® NCHR AFM probe. All images were acquired at a 0.3 Hz scan rate in tapping mode.

Figure 2 from “Effective gamma-ray sterilization and characterization of conductive polypyrrole biomaterials”: (a) Atomic force micrographs of PPy and γ-PPy samples irradiated with different doses of gamma-ray. (b) Average roughness (root mean square) of PPy and γ-PPy samples. NanoWorld Pointprobe NCHR AFM probes were used for the imaging.
Figure 2 from “Effective gamma-ray sterilization and characterization of conductive polypyrrole biomaterials”: (a) Atomic force micrographs of PPy and γ-PPy samples irradiated with different doses of gamma-ray. (b) Average roughness (root mean square) of PPy and γ-PPy samples.

*Semin Kim, Jin-Oh Jeong, Sanghun Lee, Jong-Seok Park, Hui-Jeong Gwon, Sung In Jeong, John George Hardy, Youn-Mook Lim, Jae Young Lee
Effective gamma-ray sterilization and characterization of conductive polypyrrole biomaterials
Nature Scientific Reports, volume 8, Article number: 3721 (2018)
DOI: https://doi.org/10.1038/s41598-018-22066-6

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