{"id":1512,"date":"2019-10-04T12:48:47","date_gmt":"2019-10-04T11:48:47","guid":{"rendered":"https:\/\/www.nanoworld.com\/blog\/?p=1512"},"modified":"2023-04-18T12:59:25","modified_gmt":"2023-04-18T11:59:25","slug":"a-short-peptide-hydrogel-with-high-stiffness-induced-by-310%e2%80%90helices-to-%ce%b2%e2%80%90sheet-transition-in-water","status":"publish","type":"post","link":"https:\/\/www.nanoworld.com\/blog\/a-short-peptide-hydrogel-with-high-stiffness-induced-by-310%e2%80%90helices-to-%ce%b2%e2%80%90sheet-transition-in-water\/","title":{"rendered":"A Short Peptide Hydrogel with High Stiffness Induced by 310\u2010Helices to \u03b2\u2010Sheet Transition in Water"},"content":{"rendered":"\n

In the article \u201cA Short Peptide Hydrogel with High Stiffness Induced by 310<\/sub>\u2010Helices to \u03b2\u2010Sheet Transition in Water\u201d by Shu Hui Hiew, Harini Mohanram, Lulu Ning, Jingjing Guo, Antoni S\u00e1nchez\u2010Ferrer, Xiangyan Shi, Konstantin Pervushin, Yuguang Mu, Raffaele Mezzenga and Ali Miserez, a short biomimetic peptide composed of eight amino acid residues derived from squid sucker ring teeth proteins is demonstrated to form hydrogel in water without any cross\u2010linking agent or chemical modification and exhibits a stiffness on par with the stiffest peptide hydrogels.
Their study broadens the range of secondary structures available to create supramolecular hydrogels, and introduces 310\u2010<\/sub>helices as transient building blocks for gelation via a 310\u2010<\/sub>to\u2010\u03b2\u2010sheet conformational transition.*

The AFM images presented in this study were obtained in soft tapping mode using NanoWorld Pointprobe\u00ae NCSTR<\/a> AFM probes. <\/p>\n\n\n\n

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Figure 1 from \u00abA Short Peptide Hydrogel with High Stiffness Induced by
310\u2010<\/sub> Helices to \u03b2\u2010Sheet Transition in Water\u201d by Shu Hui Hiew et al.
Structural features and physico\u2010chemical properties of GV8 peptide hydrogel observed with time\u2010series spectroscopy measurements during gelation
b) AFM amplitude profile of dried GV8 hydrogel with fibers of \u22486\u201310 nm height. <\/figcaption><\/figure>\n\n\n\n

*Shu Hui Hiew, Harini Mohanram, Lulu Ning, Jingjing Guo, Antoni S\u00e1nchez\u2010Ferrer, Xiangyan Shi, Konstantin Pervushin, Yuguang Mu, Raffaele Mezzenga, Ali Miserez
A Short Peptide Hydrogel with High Stiffness Induced by 310\u2010<\/sub>Helices to \u03b2\u2010Sheet Transition in Water<\/strong>
Advanced Science 2019, 1901173
Doi: https:\/\/doi.org\/10.1002\/advs.201901173<\/p>\n\n\n\n

Please follow this external link to read the full article: https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/advs.201901173<\/a><\/p>\n\n\n\n

Open Access: The article \u00ab A Short Peptide Hydrogel with High Stiffness Induced by 310<\/sub>\u2010Helices to \u03b2\u2010Sheet Transition in Water \u00bb \u201d by Shu Hui Hiew, Harini Mohanram, Lulu Ning, Jingjing Guo, Antoni S\u00e1nchez\u2010Ferrer, Xiangyan Shi, Konstantin Pervushin, Yuguang Mu, Raffaele Mezzenga and Ali Miserez is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other thirdparty material in this article are included in the article\u2019s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article\u2019s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http:\/\/creativecommons.org\/licenses\/by\/4.0\/. <\/p>\n\n\n\n